Integrating multi-attribute similarity networks for robust representation of the protein space

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Integrating multi-attribute similarity networks for robust representation of the protein space

MOTIVATION A global view of the protein space is essential for functional and evolutionary analysis of proteins. In order to achieve this, a similarity network can be built using pairwise relationships among proteins. However, existing similarity networks employ a single similarity measure and therefore their utility depends highly on the quality of the selected measure. A more robust represent...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2006

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btl130